Midnight In The Desert — drugs

FDA approves 1st ‘living drug’ to treat cancer in the US

Posted by K R on

FDA approves 1st ‘living drug’ to treat cancer in the US

The Food and Drug Administration has approved the first-ever gene therapy to treat cancer in the US. The treatment offers a totally new approach to fighting the disease and could lead to novel treatments of other serious and life-threatening maladies. On Wednesday, the FDA approved a new leukemia treatment from the Swiss pharmaceutical company Novartis, which the agency said is “the first gene therapy available in the United States.” The treatment, called Kymriah, is a “genetically-modified autologous T-cell immunotherapy,” where each dose is created by using the patient’s own T-cells, a type of white blood cell known as a lymphocyte....

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Here's Why You Shouldn't Self-Medicate Mental Illness With DMT

Posted by K R on

Here's Why You Shouldn't Self-Medicate Mental Illness With DMT

In this era of brain augmentation, nootropics, microdosing, and alternative medicine, it might seem tempting to take your mental health concerns into your own hands. But a case report about a man who tried to DIY mental health treatment with DMT, published in the Journal of Psychoactive Drugs on July 7, might convince you to exercise caution when it comes to experimenting with psychotropic drugs. This cautionary tale involves a former psychiatrist who tried to treat his treatment-resistant bipolar depression with the powerful psychedelic N,N-Dimethyltryptamine — better known as DMT — with dire results. The unnamed patient, a 40-year-old retired...

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400 People Microdosed LSD for a Month in the Name of Science

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400 People Microdosed LSD for a Month in the Name of Science

In late 2015, Rolling Stone wrote about an unlikely "hot new business trip" taking Silicon Valley by storm: microdosing LSD. It was the post that launched a thousand blogs, and in the year and a half since, nary a media outlet hasn't written about microdosing at least once. As its name suggests, microdosing involves regularly taking hits of acid that are so small (between 1 and 10 micrograms, or below a tenth of a regular dose) that users won't feel any of the trippy effects. Still, the microdosing community swears by the practice and reports boosted creativity, energy and a...

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Drug shows promise in reducing Alzheimer’s

Posted by K R on

Drug shows promise in reducing Alzheimer’s

In what some experts are hailing as a major breakthrough in the field of Alzheimer’s research, a new investigational drug was found to reduce the disease’s hallmark plaques— potentially slowing cognitive decline and preventing the disease. Researchers cautioned, however, that the study was an early test for safety, and the drug needs to be tested further. Alzheimer’s disease is marked by amyloid plaques, which are believed to be the main culprit in the most common form of dementia. Build-up of amyloid proteins leads to plaques, which blocks cell-to-cell signaling. In the trial by Biogen, researchers tested an antibody to see...

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Scientists Developed a Way to Make DMT Trips Last Longer Than Ever

Posted by K R on

Scientists Developed a Way to Make DMT Trips Last Longer Than Ever

Known in drug lore as "the businessman's trip" for its lunch-break-size 15-minute duration, DMT (N,N-dimethyltryptamine) is infamous for blasting its users into vivid alien worlds. It's among the most literally hallucinogenic of all the psychedelics, and now a pair of veteran researchers have proposed a method to safely extend the experience beyond its normal length. Dr. Rick Strassman and Dr. Andrew Gallimore published their paper in Frontiers in Psychology last month, under the name "A Model for the Application of Target-Controlled Intravenous Infusion for a Prolonged Immersive DMT Psychedelic Experience." Its implications could turn DMT research on its head, allowing...

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